Residents from the 15 county area are fortunate to have DuBois Regional Medical Center to provide premier patient care services.  DRMC's services include its award winning Heart Center, Neonatal Intensive Care Unit, Women's Health Center, Rehabilitation Center, Behavioral Health Center and Hahne Regional Cancer Center. DRMC was selected as one of the nation's 100 Top Hospitals by Thomson Reuters. Patients can also receive care locally at Brookville Hospital, Clearfield Hospital and Elk Regional Health Center.

Two continuing care communities in DuBois offer the complete spectrum from independent living, assisted living to skilled nursing.  DuBois Continuum of Care Community and Christ the King Manor provide rehabilitation services and special units for residents with Alzheimer's disease. Mountain Laurel Nursing & Rehabilitation Center provides long term skilled nursing and short term rehabilitation care in Clearfield.

Home health agencies are a growing industry with several companies to choose from: Guardian Home & Community Services, Inc., Helpmates, Inc., Tri County Nursing, LLC, and Home Instead Senior Care.